Anti-CaMK II (δ 1-δ 4), Rabbit-Poly <Anti-Cam Kinase II>
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Anti-CaMK II (δ 1-δ 4), Rabbit-Poly <Anti-Cam Kinase II>

Price: $565.00
  • Item #: KY041
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Anti-CaMK II (δ 1-δ 4), Rabbit-Poly <Anti-Cam Kinase II>

Cat. No. KY041

Store at -20°C

Size 200µg

Antigen- Rat

Host Animal- Rabbit 

Cross Reactivity- Rat

Application- IHC, Western Blot

Unlabeled 

Purification- APu

 

 

Description 

Ca2+/calmodulin-dependent protein kinase II (CaM kinase II) may play key roles in various Ca2+ induced cellular functions. Interestingly, many kinds of isoforms have been identified in various tissues or cells. Recently, it has been revealed that some isoforms are located in specific regions in the cells, so it is speculated that these isoforms have physiologically particular functions in each region. There are four different isoforms such as α,β,γ and δ. This antibody reacts with δ1‐δ4 splice variants. Immunochemical studies indicate that δ2 is expressed in various tissues or cells such as insulinoma cells and that δ3 is abundant in the nucleus in cerebellar granule cells. These results suggest that δ3 is involved in Ca2+ dependent gene expression. This antibody has been proven to be useful for immunoblotting and immunohistochemistry

 

References 

1. Matumono,K., Ebihara,K., Yamamono, H., Tabuchi, H., Fukunaga, K., Yasunami, M., Ohkubo, H., Shichiri, M.,Miyamoto, E: J.Biol.Chem.,274,2053-2059 (1999)

2. Tabuchi, H., Yamamoto, H., Matsumoto, K., Ebihara, K., Takeuchi, Y., Fukunaga,K.,Hiraoka,H., Sakai Y., Shichiri,M., Miyamoto,E. :Endocrinology,141,2350-2360 (2000)

3. Takeuchi, Y., Yamamoto. H., Matsimoto, K., Kimura, T., Katsuragi, S., Miyakawa, T., Miyamoto, E.: J.Neurochem.,72.815-825 (1999)

4. Takeuchi, Y., Yamamoto, H., Miyakawa, T., Miyamoto, E.: J. Neurochem.,74,1913-1922 (2000)

5. Takeuchi, Y., Yamamoto, H., Fukunaga, K., Miyakawa, T., Miyamoto, E. : J. Neurochem.,74,2557-2567 (2000) 

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