Anti-EID1, Mouse-Mono(#26) (Cat. No. 71-185)
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Anti-EID1, Mouse-Mono(#26) (Cat. No. 71-185)

Price: $330.00
  • Item #: 71-185
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Anti-EID1, Mouse-Mono(#26)

Cat. No. 71-185 

Store at -20°C 

Size 50µg

Antigen- Human

Host Animal- Mouse

Cross Reactivity- Human/ Mouse/ Rat

Application- ELISA, Western Blot

Unlabeled

Purification- Pu

Clone- 26

Class- IgG


 

Description 

EID1 (EP300 interacting inhibitor of differentiation 1) encodes a 21 kDa protein, which interacts with RB1 and EP300 and acts as a repressor of MYOD1 transcription. EID1 inhibits EP300 and CBP histone acetyltransferase activity. It may be involved in coupling cell cycle exit to the transcription of genes required for cellular differentiation. 

 

References

1. MacLellan WR et al “A novel Rb- and p300-binding protein inhibits transactivation by MyoD” Mol Cell Biol 20:8903-8915 (2000) PMID: 11073990

2. Nguyen DX et al “Acetylation regulates the differentiation-specific functions of the retinoblastoma protein” EMBO J 23: 1609-1618 (2004) PMID: 15044952 

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