Anti-Macrophage Scavenger Receptor, Human, Mouse-Mono (SRA-E5)
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Anti-Macrophage Scavenger Receptor, Human, Mouse-Mono (SRA-E5)

Price: $635.00
  • Item #: KT022
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Anti-Macrophage Scavenger Receptor, Human, Mouse-Mono (SRA-E5) <Anti-CD204>
Cat. No. KT022
Store at -20°C
Size 50µg
Antigen- Human
Host Animal- Mouse
Cross Reactivity- Human
Application- IHC, Western Blot
Unlabeled 
Purification- APu
Clone- SRA-E5 

Class- IgG

 

 

Description

Macrophage scavenger receptor (MSR-A: CD204) was identified in the search for the receptor molecules that are implicated in the pathological deposition of cholesterol during atherogenesis through receptor-mediated uptake of modified low density lipoproteins (LDL). MSR-As possess a wide range of ligand-binding specificities and recognize a variety of molecules such as modified LDL including acetylated LDL, oxidized LDL, advanced glycation end products (AGE), polyribonucleotides such as poly G and poly I and bacterial surface lipids including lipopolysaccharide and lipoteicoic acid. This antidody was produced from the mouse immunized with recombinant protein of human type I MSR-A ,and has been proved to be useful for the immunoblotting and immunohistochemistry. This antibody is useful tools for the study of MSR in atherogenesis and various other pathological conditions in humans and animal species. 

 

Reference

1. Takeya M., Tomokiyo R., Jinnouchi K., Sakaguchi H., et al: Macrophage Scavenger Receptors: Structure, Function and Tissue Distribution: Acta Histochem. Cytochem. 32(1):47-51,1999

2. Tomokiyo R., Jinnouchi K., Honda M., Wada Y., Hanada N., Hiraoka T., Suzuki H., Kodama T., Takahashi K., Takeya M.: Production, characterization, and interspecies reactivities of monoclonal antibodies against human class A macrophage scavenger receptors: Atherosclerosis, 2001, in press.

3. Takeya M., Tomokiyo R., Jinnouchi K. Honda M. et al: CD204: Macrophage scavenger receptor, a new differentiation marker for macrophages: part 9 Myeloid Cells, New CD Antigens, Leucocyte Typing Ⅶ, Oxford Univ. Press, 2001, in press.

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