Anti-Nob1 (S.cerevisiae) antibody, affinity purified
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Anti-Nob1 (S.cerevisiae) antibody, affinity purified

Price: $420.00
  • Item #: 62-211
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Anti-Nob1 (S.cerevisiae) antibody, affinity purified
Cat. No. 62-211
Store at -20°C
Size 100µl
Antigen- Yeast 
Host Animal- Rabbit 
Cross Reactivity- Yeast
Application- IP, Western Blot 
Unlabeled 
Purification- APu


 

 

Description 

The 26 S proteasome is a protein complex with a molecular mass of 2,000 kDa. It is essential not only for eliminating damaged or misfolded proteins but also for degrading short lived regulatory proteins involved in cell cycle regulation, DNA repair, signal transduction, apoptosis, and metabolic regulation (1). Nob1p is essential nuclear protein required for biogenesis of the 26S proteasome (2). Nob1p is speculated to serve as a chaperone to join the 20S proteasome with the 19S regulatory particle in the nucleus and to be degraded upon the maturation of the 26S proteasome (3). Nob1p is composed of 459 amino acid residues.

 

References 

1. Tone Y et al “Nob1p, a new essential protein, associates with the 26S proteasome of growing Saccharomyces cerevisiae cells” Gene 243:37-45 (2000) PMID: 10675611

2. Tone Y and Toh-e A “Nob1p is reqired for biogenesis of the 26S proteasome and degraded upon its maturation in Saccharomyces cerevisiae” Genes & Dev 16 :3142-3157 (2002) PMID: 12502737 

*This product was used in ref. 1 and 2

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