Anti-Rad52 antibody, affinity-purified rabbit polyclonal
Cat. No. 70-015
Store at -20°C
Size 50µg
Host Animal- Rabbit
Unlabeled
Purification- APu
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Description
Human Rad52 protein is a functional and structural homolog of yeast Rad52 protein which plays a major role in genetic recombination and recombination repair by mediating strand annealing between homologous DNA strands (1). Rad51 functionally and physically interacts with Rad51 in recombination processes. It also interacts with oncogenes and tumor suppressors for the maintenance of genome stability (1). The product was prepared by immunizing rabbit with the full-size recombinant Rad52 protein expressed in E. coli and affinity-purified with the recombinant Rad52. Using this anti-serum, Rad52 protein (46 kD) was detected by Western blotting (Fig 1) at 46 kD position . This antibody was successfully used for immunoprecipitation assay (Fig. 2).
References
Friedberg EC et al DNA Repair and Mutagenesis 2nd ed., ASM Press (2006)
