Anti-SARS spike glycoprotein antibody (clone 3A2)
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Anti-SARS spike glycoprotein antibody (clone 3A2)

Price: $375.00
  • Item #: 65-101
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Anti-SARS spike glycoprotein antibody (clone 3A2)
Cat. No. 65-101
Store at -20°C
Size- 50µg
Host Animal- Mouse
Unlabeled 
Clone- 3A2 

 

 

Description 

A novel type of coronavirus has been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome). Spike glycoprotein is essential for the infection and directly binds to the virus receptor, ACE2 (Angiotensin-Converting Enzyme 2). Hybridoma 3A2 has been isolated by injecting mouse with SARS virus and as the clone which produces antibody that specifically reacts with the virus-infected cell (Fig. 1), in the laboratory of Prof. K. Ikuta of Osaka University. Monoclonal antibody 3A2 recognizes the spike protein consisting of 1181 amino acids, which migrates at 200 kDa position on SDS-PAGE (Fig. 2) due to its glyco-chains.

 

References 

1. Satija N and Lal SK “The molecular biology of SARS coronavirus” Ann N Y Acad Sci 1102: 26-38 (2007) PMID: 17470909

2. Yamate M et al “Establishment of Vero E6 cell clones persistently infected with severe acute respiratory syndrome coronavirus” Microbes and Infect 7:1530-1540 (2005) PMID: 16269264

*This product has been used in reference 2. 

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