N1, N12-Diacetylspermine, Urinary, ELISA Kit<DiAcSpm, ELISA Kit>
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N1, N12-Diacetylspermine, Urinary, ELISA Kit<DiAcSpm, ELISA Kit>

Price: $865.00
  • Item #: KK073
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N1, N12-Diacetylspermine, Urinary, ELISA Kit <DiAcSpm, ELISA Kit>
Cat No. KK073
Storage -20c
Size 1 Kit

 

 

  

 

                                                        A new cancer marker

                              Urinary Diacetylspermine/Diacetylspermidine ELISA kit

 

 

Sensitivity : 50.0nM.
Recently two diacetyl-derivatives, N1, N12-diacetylspermine and N1, N8-diacetylspermidine, were found to be excreted in urine and form 0.6% and 1.4% of total polyamines respectively.
Comparing urine of diseased person with urine of healthy person, some reports suggested the possibility that diacetyl-derivatives correlate to the status of disease more closely than total amount of polyamines.
This kit is convenient to quantify amount of urinary diacetylspermine by using ELISA method.

 

N1,N12-Diacetylspermine (DiAcSpm)

 

 

N1,N8-Diacetylspermidine (DiAcSpd)

 

 

 

Polyamines are generally believed to function both in protein synthesis and DNA synthesis

leading to control cell proliferation. In 1971, it was reported that total amount of urinary polyamines

elevated in cancer patients. Quantitative kits of urinary polyamines were already developed

and utilized as a general biochemical examination.


Recently two diacetyl-derivatives, N1, N12-diacetylspermine (DiAcSpm) and N1, N8-diacetylspermidine (DiAcSpd),

were found to be excreted in urine and form 0.6% and 1.4% of total polyamines respectively.
Comparing urine of diseased person with that of healthy person, some reports suggested

a possibility that diacetyl-derivatives correlate to the status of disease more closely than

total amount of polyamines.


Our ELISA kits are convenient to quantify urinary DiAcSpm or DiAcSpd.

<Synthetic Pathway of DiAcSpm and DiAcSpd>

 

<Assay Principle>

<Specs>

 

#KK073 Urinary N1, N12-diacetylspermine (DiAcSpm) ELISA kit

Standard Curve Range : 6.25 - 200 nM

Detection Limit : 12.5 nM

Minimum Sample Dilution : x 4

Sample : Urine 

 

#KK123 Urinary N1, N8-diacetylspermidine (DiAcSpd) ELISA kit

Standard Curve Range : 9.375 - 600 nM

Detection Limit : 18.75 nM

Minimum Sample Dilution : x 2

Sample : Urine

 



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